Astrocytic and microglial response and histopathological changes in the brain of horses with experimental chronic Trypanosoma evansi infection.

Immunohistochemical characterization of mononuclear cells and MHC II expression in the brain of horses with experimental chronic Trypanosoma evansi infection.

An histochemical and immunohistochemical study was carried out to evaluate the mechanisms of immune response of horses experimentally infected by Trypanosoma evansi. For this purpose the HE histochemical stain and the avidin biotin peroxidase method were used. To determine the presence and immunoreactivity of immune cells we used anti-major histocompatibility complex II antibodies. Cellular inf...

Evaluation of Humoral Immune Response to Foot-and-Mouth Disease Vaccination in Experimentally Infected Guinea Pigs with Trypanosoma evansi

EXPERIMENTAL Trypanosoma Evansi INFECTION IN ALBINO MICE – A HISTOPATHOLOGICAL STUDY

Histopathological changes were studied in Swiss albino mice (N:36) which were challenged with the South Indian local strain of Trypanosoma evansi. Each animal was infected with 5×105 trypanosomes intraperitoneally. The animals were examined daily for development of clinical signs and infection status by wet blood-fi lms made from the tail veins. The infected mice were dull and depressed from tw...

The Histopathological Changes and Immunohistochemical Findings of Acute, Chronic Nonlupoid and Chronic Lupoid Types of Cutaneous Leishmaniasis

Background & Aims: Dry type localized cutaneous Leishmaniasis due to Leishmania tropica is one of the most prevalent cutaneous parasitic infections in Kerman province. It seems that cellular immune response and the nature of immune inflammatory cells comprising the inflammatory background play a determinant role in this infection. Methods: Skin biopsies of 53 patients with acute(<2 years durati...

Physio-biochemical Alterations in Trypanosoma Infected Dog

Trypanosomosis is a disease caused by a flagellate protozoan known as Trypanosoma evansi, transmitted by hematophagous insects. It parasites showed a large diversity of mammalian hosts. Dogs may show clinical changes such as weight loss, progressive weakness, anorexia, anemia, intermittent fever, conjunctivitis, swelling of limbs and increased of superficial lymph nodes. Treatment of trypanosom...